La metformina es un agente oral hipoglucemiante que se utiliza en el tratamiento de la diabetes mellitus tipo 2. Los resultados del UK Prospective Diabetes. ACIDOSIS LACTICA Es una forma de acidosis metabólica caracterizada por los niveles elevados de acido láctico Niveles bajos de bicarbonato sérico. PDF | Introducción La acidosis láctica se diagnostica mediante la acidosis metabólica, que se asocia a una elevada concentración sérica del lactato.

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Cuando la acidosis persiste y el paciente empeora suele sufrir un “shock” y muere si evoluciona sin tratamiento. After taking non-steroidal anti-inflammatory drugs, the patient developed vomiting, abdominal pain, diarrhea, oliguria, and lactic acidosis.

Comments 0 Please log in to add your comment. Metformin is an antihyperglycemic agent commonly used in diabetic patients.

Present to your audience. Drugs ;58 Suppl 1: The management of metformin overdose. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes UKPDS Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus.

Papel del nefrólogo en la acidosis láctica grave por metformina

Nephrol Dial Transplant 8: N Engl J Med ; 4: Check out this article to learn more or contact your system administrator. Constrain to simple back and forward steps. Delete comment or cancel. Add a personal note: Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.


Copy code to clipboard. Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus.

Send this link to let others join your presentation: Please log in to add your comment. See more popular or the latest prezis. Una acidoxis antes de su ingreso tuvo un cuadro sincopal mientras trabajaba en el campo. We present the case of a patient with hypertension treated with indapamide and captopril and type 2 diabetes mellitus treated with insulin and metformin.

Papel del nefrólogo en la acidosis láctica grave por metformina

Neither you, nor the coeditors you shared it with will be able to recover it again. A firewall is blocking access to Prezi content. Stand out and be remembered with Prezi, the secret weapon of great presenters. Houston, lacticaa have a problem! J Clin Endocrinol Metab ;81 Ortega Carnicer J, Ambr??

Si la enfermedad evoluciona sin tratamiento el pacientre sufre un shock y muere. Lactic acidosis is an uncommon side effect of metformin use, which is more likely to arise in patients with certain predisposing factors. Send the link below via email or IM Copy.

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Metformin-associated lactic acidosis in an intensive care unit. Crit Care ;12 6: We use cookies to help provide and enhance our service and tailor content and ads. Standards of medical care in diabetes By continuing you agree to the use of cookies. However, in some patients, specially those with comorbidities, metformin can provoke severe lactic acidosis with high morbimortality.

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Los electrones son transferidos por NADH y las reacciones son catalizadas por la lactato deshidrogenasa. Do you really want to delete this prezi? Med Intensiva ;31 9: It is very effective and is able to reduce the plasma glucose and HbA 1C.

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