Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional. Mandible / maxilla – Benign tumors / tumor-like conditions: adenomatoid odontogenic tumor.

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Regional lymph node dissection should be considered and performed selectively.

Adenomatoid odontogenic tumor, an uncommon tumor

Adenomatoid odontogenic tumor arising from the mandibular molar region: The granular cells are a transitional or matured phase in the life cycle of ameloblastomas, starting with normal stellate reticulum-like cells, leading to a production of granules and finally resulting in degeneration and the formation of cystic areas, differing from the aggressive tumor nature reported previously. By using this site, you agree to the Terms of Use and Privacy Policy.

Conservative treatment is adequate because the tumor is not locally invasive, is well encapsulated, and can be easily adenomatois from the bone.

The origin of AOT is controversial, but many author believe in odontogenic source. View at Google Scholar A.

However, the available odontogeic in the literature suggest that some extrafollicular AOTs may arise as a secondary phenomenon within pre-existing odontogenic cysts or cystic tumors. Maxillary arch is the predilection site of occurrence, most commonly associated with an unerupted maxillary canine. In the past, similar lesion with the terminology like adeno ameloblastoma has resulted in unnecessary mutilating surgery.

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Since this tumor shows considerable clinical and radiographical similarities with a dentigerous cyst, a differential diagnosis is necessary. Open in a separate window. The intraoral periapical radiograph is the best radiograph to show radiopacities in AOT as discrete foci having a flocculent pattern within radiolucency even with minimal calcified deposits. Odontohenic the variants of ameloblastomas, approximately Co-expression of hepatocyte growth factor and c-met in epithelial odontogenic tumors.

Int J Clin Exp Pathol ; 5: Radiographically, AOT adejomatoid looks like a dentigerious cyst. J Sci Soc ; Adenomatoid odontogenic tumor associated with dentigerous cyst in posterior maxilla: J Oral Pathol Med.

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Ameloblastin expression in rat incisors and human tooth ldontogenic. Rom J Morphol Embryol ; The maxillary arch is the predominant site of occurrence, being almost twice as frequent as that of the mandible, and the anterior part of the jaw is more frequently involved than the posterior part. Types of adenomatoid odontogenic tumor AOT ldontogenic an uncommon, progressively growing, and asymptomatic benign non-invasive lesion that occurs twice as often in females and usually in the second decade of life.

Basaloid squamous cell carcinoma versus basal cell ameloblastoma. In Harbitz of Norway reported a case of cystic adamantoma.

OPG showing circumscribed radio-lucent lesion with calcifications and impacted teeth.

On the other hand, tumor necrosis factor-related apoptosis-inducing ligand TRAIL and TRAIL receptor are diffusely expressed in ameloblastomas and are possibly involved in the neoplastic transformation of odontogenic epithelium. It is necessary to pay special attention, especially in elderly patients, and to carry out further clinical, radiological, and pathohistological diagnostic procedures, such as immunohistochemical analysis.


Podoplanin expression profiles characteristic of odontogenic tumor-specific tissue architectures. Abstract Ameloblastomas and adenomatoid odontogenic tumors AOTs are common epithelial tumors of odontogenic origin.

Differential diagnosis of this image revealed a first dentigerous cyst, an adenomatoid odontogenic tumor, and a calcifying odontogenic cyst. Dentigerous cyst Odontogenic cyst. Surgical exposure of lesion Click here to view.

Adenomatoid odontogenic tumor – Wikipedia

The rate of occurrence was higher in males, and the most common site of occurrence was the mandible. Adenomatkid odontogenic tumour adenoameloblastoma.

The axial slides of CBCT Figure 3 showed a well-circumscribed radiolucent lesion with well-defined radiopaque border extending horizontally from maxillary midline to the distal margin of the second premolar and vertically from the nasal base to the midpart of the roots of teeth 21 and Ameloblastoma with basal cell carcinoma-like feature emerging as a nasal polyp. These tumors are predominantly found in young female patients, are more often located in the maxilla, and are typically associated with an unerupted permanent tooth.

It is not possible to distinguish conventional intraosseous ameloblastomas from malignant ameloblastomas according to histopathologic features. Pindborg H, Kramar IR.

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